A new EU funded project, in the framework of Horizon 2020 programme will create innovative and enhanced nature-based solutions to create closed and sustainable urban water loops. NICE will implement nature-based solutions in cities across Spain (Algeciras, Benalmádena, Madrid, Talavera de la Reina and Vigo), France (Lyon), Poland (Gdansk), Colombia (Pereira), Egypt (Cairo), Italy (Turin) and Denmark (Aarhus). NICE nature-based solutions will treat wastewater and greywater, help restore river basins, capture stormwater and address combined sewer overflow. The solutions will entail green walls and vegetable roofs, rain gardens and hybrid subsurface wetlands. NICE will use the latest technologies such as bioaugmentation and innovative reactive media to enhance the nature-based solutions further.